Professor Stephen Hawking has joined David Walliams for a special version of the classic Little Britain sketch Lou and Andy.

The pair teamed up for a one-off comedy scene that will be screened as part of Comic Relief’s Red Nose Day on March 13, according to The Sun.

David returns as his carer character Lou, but rather than being joined by usual sidekick Matt Lucas as the crafty Andy Pipkin in his wheelchair, this time Professor Hawking stars.

Lou and Andy
David and Matt as Lou and Andy (PA)

Andy was famous for his “I want that one” catchphrase in the sketch show which ran from 2003 to 2006.

Catherine Tate, who appeared in the original show, also joins the sketch as a nun and the trio were seen filming at St John’s College, Cambridge University, where Professor Hawking is a director of research.

A stunt man stood in for the physicist, who has motor neurone disease, in the morning rehearsals.